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KMID : 0378019660090080065
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New Medical Journal
1966 Volume.9 No. 8 p.65 ~ p.84
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Clinical Observations on Bone Tumors
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鄭仁熙/Chung, In Hee
申廷淳/金南鉉/Shin, Jung Soon/Kim, Nam Hyun
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Abstract
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This report is based on 117 cases of bone tumor who were seen and treated at our department during the 6 year and 11 months period from January, 1957 to November, 1963. The study includes clinical, pathologic and radiologic observations on our series of bone tumor.
Fourty-two cases (35.9%) of benign tumors included osteochondroma -10 cases (23,8%), osteoma - 7 cases (16.7%), benign giant-cell tumor-6 cases (14.3%), osteoid osteoma and enchondroma - 5 cases (11.9%) each, fibrous dysplasia and solitary bone cyst - 3 cases (7.1%) each, multiple cartilaginous exostosis - 2 cases (4.8%), and multiple enchondromatosis - 1 case (2.4%).
Seventy-five cases (64.1 %) were malignant tumors. These included metastatic cancer - 32 cases (42.7%), osteogenic sarcoma - 25 cases (33.3%), malignant giant-cell tumor and multiple myeloma - 4 cases (5.3%) each, chondrosarcoma, lymphosarcoma, Ewing´s sarcoma and fibrosarcoma - 2 cases (2.7%) each, juxtacortical osteogenic sarcoma and -reticulum-cell sarcoma - 1 case (1.3%) each.
The results may be summarized as follows:
1) In our series of bone tumors, the ratio between benign and malignant tumors was 42:75, a greater incidence of malignant tumors.
2) Osteochondroma was the most frequently encountered benign bone tumor - 10 cases (23.8%).
3) Excluding metastatic cancer of bone, osteogenic sarcoma was the most frequently encountered malignant tumor - 25 cases (33.3%)
4) Ten cases of giant-cell tumor were divided into two types - benign and malignant. The ratio was 6:4.
5) The average age for cases of giant-cell tumor was 33.8 years and the male to female ratio was 2:8.
6) The common sites for giant-cell tumor were the distal end of the radius (4 cases), and around the knee joint (the distal end of the femur - 2 cases, the proximal end of the tibia - 2 cases).
7) Among 10 cases of giant-cell tumor, one case (10%) showed malignant change with recurrence 8 months after the primary operation of curettage and bone chip graft.
8) Among 3 cases of solitary bone cyst, recurrence was noted in one case (33.3%) 10 months after the curettage and bone chip graft.
9) In 25 cases of osteogenic sarcoma, the peak incidence was in the age group from 20 to 29 years - 9 cases (36%). Two cases were under 10 years of age. The average age was 28.4 years.
10) The sex distribution of osteogenic sarcoma was 20 males (80%) and 5 females (20%), a male predominance.
11) The most common sites for osteogenic sarcoma were the distal femur and the proximal tibia - 17 cases (68%).
12) In 32 cases of metastatic cancer, the peak incidence was from 40 to 49 years - 13 cases (41%). The average age was 50.2 years.
13) There were 20 males (62.5%) and 12 females (37.5%), a male majority, which had metastatic cancer.
14) In the cases of metastatic cancer, there were multiple lesions in 18 cases (56.2%) and single lesions in 14 cases (43.8%).
15) The most common site for metastasis was the spine - 17 cases. 38 vertebral bodies were involved.
16) Among 39 cases of primary malignant tumor (exclusive of multiple myeloma), 11 cases (28.2%) had had a significant injury just prior to the onset of the tumor.
17) In our series of primary malignant tumor, because of the lack of cooperation of patients we could not present the five-year survival rate. Also the duration of the follow-up is too short as yet.
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KEYWORD
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